【Scientific information】
Research and Development Department, Sun Chlorella Corporation
Safety study of overdose of tablets containing astaxanthin and crocetin in healthy adults
Journal of Nutritional Food Vol. 12 No. 1
The results of the previously conducted clinical study on the safety of combined
astaxanthin/crocetin tablets were recently been published in an academic journal, as
reproduced below.
- Study Objectives
- The safety of combined astaxanthin/crocetin tablets was evaluated in human subjects for one month.
- Method of experiments
- Thirty-six healthy adults of both sexes took combined astaxanthin/crocetin tablets (each
tablet containing 0.6 mg astaxanthin and 0.75 mg crocetin) via the oral route for 4 weeks.
Volunteers were divided into three groups according to dose: 5 tablets/day; 10 tablets/day;
and 30 tablets/day. Each subject visited the hospital at four times (at the start of the
study, 2 and 4 weeks after the start of the study, and 2 weeks after the end of the study) to
undergo examination and checks. These involved physical examination (blood-pressure
measurement) laboratory tests (hematology) and a questionnaire survey of subjective
symptoms.
- Results
- No parameter showed a marked change and no adverse event was seen after intake of the
test product. The results endorse the safety of taking combined astaxanthin/crocetin
tablets for periods up to 4 weeks at a dose level of up to 30 tablets per day.
Specifications of the article
- Journal:
- Journal of Nutritional Food Vol. 12 No. 1, 1–12
- Title:
- Safety study of overdose of tablets containing astaxanthin and crocetin in healthy adults
- Authors:
- Yukari Arakawa1), Masaki Fujishima1), Toru Mizoguchi1), Isao Takehara2), Ikuo Fukuhara3)
- Affiliation:
- 1) Sun Chlorella Corporation, 2) New Drug Development Research Center, Incorporated, 3) Fukuhara Hospital
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